The significance of end-user computing in business applications lies in empowering users to create and manage their own computing solutions without needing extensive IT support. This approach boosts productivity and fosters innovation by enabling individuals to develop customized applications and automate tasks. It also reduces the burden on IT departments, allowing them to focus on critical infrastructure and security. Furthermore, end-user computing enhances user satisfaction by providing tailored solutions that meet specific business needs, ultimately leading to improved operational efficiency.