The main benefit of using microservices in software architecture is enhanced scalability and flexibility. Microservices break down a monolithic application into smaller, independently deployable services that can be developed and scaled individually. This modular approach allows teams to work concurrently, making it easier to implement updates and new features without impacting the entire system. Furthermore, microservices can be developed using different technologies, enabling organizations to choose the best tools for specific functionalities and improving overall maintainability.