The record holder for most points scored in a single basketball game is Wilt Chamberlain, who scored 100 points on March 2, 1962. This iconic achievement remains unmatched in NBA history and emphasizes Chamberlain's dominance on the court during his playing days. His incredible performance highlighted his scoring ability and strength, setting a benchmark that still captivates basketball fans today. The feat is often referenced in discussions about the greatest performances in sports history.