The creature that guards the golden apples in mythology is the Hesperides, often depicted as dragon-like or monstrous beings. In Greek mythology, they are tasked with protecting the golden apples that bestow eternal life. The apples were a gift from Gaia to Hera and were located in a celestial garden. Their protection signifies the significance of immortality and divine blessings, as well as the challenges faced by heroes in their quests.