The ancient city famously sacked by the Vandals in 455 AD was Rome. The Vandals, a Germanic tribe known for their naval prowess, invaded Rome under their king Genseric. This event was particularly significant because it highlighted the decline of Roman power and the vulnerability of the city after centuries of dominance. The sack lasted for two weeks and was marked by widespread looting and destruction, further contributing to the perception of Rome as a once-great empire in decline. The term "vandalism" itself derives from this event, symbolizing the deliberate destruction of art and culture.