High fructose corn syrup (HFCS) has a negative impact on health due to its association with increased caloric intake and obesity rates. HFCS is often found in many processed foods and sugary beverages, leading to higher overall sugar consumption. Research links excessive intake of HFCS to various health conditions, such as insulin resistance, fatty liver disease, and metabolic syndrome. Additionally, HFCS can disrupt the body’s ability to signal when it's full, encouraging overeating. Thus, reducing HFCS consumption is essential for maintaining a healthy diet.