Guidelines for healthy weight loss typically recommend aiming for a gradual reduction of about 1-2 pounds per week. This can be achieved through a combination of dietary changes and increased physical activity. A balanced approach includes consuming fewer calories while focusing on nutrient-dense foods, such as whole grains, fruits, and vegetables. Regular exercise, particularly aerobic and strength training, supports weight loss and improves overall fitness. Setting realistic goals and tracking progress can also enhance motivation and adherence to a sustainable weight loss plan.