Prolonged sitting can have detrimental effects on metabolic health. It is associated with increased risks of obesity, type 2 diabetes, and cardiovascular diseases. When individuals sit for extended periods, energy expenditure decreases, leading to reduced calorie burning and altered lipid and glucose metabolism. This sedentary behavior can also contribute to muscle atrophy and poor posture. To combat these negative effects, incorporating regular movement breaks, standing desks, and active commuting into daily routines can enhance overall metabolic function and promote healthier living patterns.