Extreme caloric restriction can lead to various negative consequences, including nutrient deficiencies, weakened immune function, and muscle loss. When the body is deprived of adequate calories, it enters a state of starvation, slowing metabolism and potentially causing fatigue, dizziness, and irritability. Long-term restrictions can also lead to eating disorders and create an unhealthy focus on food. Ultimately, severe caloric restriction may result in severe health issues, including hormonal imbalances and increased risk of osteoporosis, negatively affecting overall well-being.