To overcome workout fatigue, effective strategies include prioritizing rest, ensuring adequate hydration, and consuming the right nutrients, particularly carbohydrates and proteins. Gradually progressing in workout intensity can also help train the body to manage fatigue. Varying workout routines to include active recovery can alleviate fatigue while enhancing endurance. Additionally, incorporating mindfulness practices can help recognize mental fatigue and combat it. Lastly, maintaining a positive mindset towards challenges can create resilience against workout fatigue.