Prolonged sitting can have several negative impacts on health, including increased risks of obesity, diabetes, and cardiovascular diseases. It can lead to poor posture and musculoskeletal discomfort, particularly in the back and neck. Extended sedentary behavior reduces metabolic rate, impacting insulin sensitivity and fat metabolism. Additionally, it can contribute to feelings of lethargy and decreased energy levels. Incorporating regular movement and standing breaks throughout the day is essential for mitigating these health risks.