Aspirants should approach synthesizing information for comprehensive answers in UPSC by prioritizing clarity and coherence. First, identifying the core question is crucial to determine the relevant points to include. Structuring answers around a clear introduction, body, and conclusion helps maintain organization. Utilizing bullet points for significant facts or statistics can enhance readability. Furthermore, integrating examples from current affairs or historical events enriches the response. Regular practice in writing structured responses and receiving feedback also sharpens this skill, leading to comprehensive, well-rounded answers.