Selecting a balanced combination of optional subjects for the Mains Examination requires careful consideration. Candidates should assess their academic strengths and interests to choose subjects they are comfortable with. It's essential to evaluate the syllabus and previous years' question patterns for each subject. Candidates should also consider the overlap between optional subjects and the General Studies papers to maximize efficiency. Additionally, understanding the availability of resources and guidance for the chosen subjects will play a crucial role in decision-making. Ultimately, choosing subjects that resonate personally can enhance motivation and performance.