Georgia O'Keeffe's artistic expressions were significantly shaped by major life events, including her time spent in the New Mexico desert and her struggle for recognition in a male-dominated art world. The death of her husband, Alfred Stieglitz, deeply affected her work, fostering a shift toward more profound emotional landscapes and a focus on nature. Her experiences shaped her distinctive style, characterized by vivid colors and bold forms, capturing both personal loss and her appreciation for the natural world's beauty.