Harriet Beecher Stowe faced considerable challenges while writing "Uncle Tom's Cabin," particularly in terms of public reception and societal norms. The novel, which exposed the harsh realities of slavery, sparked heated debates and backlash from pro-slavery advocates. Stowe encountered difficulties in gaining support from publishers and was often criticized for her emotional portrayal of enslaved individuals. Additionally, her own societal position as a woman author in the 19th century limited her influence. Despite these challenges, the book became a bestseller and was pivotal in shifting public opinion on slavery, demonstrating the power of literature in advocating for change.