Eleanor Roosevelt confronted numerous challenges during her time as First Lady of the United States, using her platform to advocate for civil rights and social reforms. Faced with personal struggles, including her husband Franklin D. Roosevelt's polio and infidelity, Eleanor transformed her discontent into activism, championing the rights of women, minorities, and the underprivileged. She broke conventions by hosting press conferences and writing a daily newspaper column, addressing controversial issues like racial segregation and labor rights. Her tenacity and dedication to social justice established her legacy as a key figure in advancing human rights in America.