Franklin D. Roosevelt's political career evolved dramatically after he contracted polio in 1921, which resulted in paralysis from the waist down. Initially, he faced challenges and public skepticism regarding his ability to lead. However, he used his condition to connect with the public, promoting policies that addressed the needs of those suffering from the economic hardships of the Great Depression. His experience with disability allowed him to emphasize the importance of social welfare programs, and he became a symbol of resilience, proving that personal struggles could translate into effective leadership and political progress.